Back in July I wrote a short article about a new UK prohormone by Fusion Supplements called AndroTest. If you don’t recall AndroTest is a cyclodextrin complex of 4-androstenediol. 4-Androstenediol is a 1 step prohormone to testosterone. In other words it’s designed to increase testosterone, which will make it a popular “test base” for UK prohormone users. In that same article I referenced previous research which showed 1 dose of an older form of 4-Androstenediol which increased total testosterone to a peak level of 1441 ng/dL.
That is just above a very high normal testosterone level, which means this product has a great potential for actually building muscle, and not just increasing testosterone enough to prevent a poor libido, and lowered energy levels.
In that same article I also presented two potential problems or unknowns that might make us hesitant as consumers on the efficacy of the product. They were as follows:
- Fusion Supplements lists the compound on the label as “Cyclo 4-AD”, which technically could mean a lot of things. It would be better if they had listed it as HBCD 4-Androstenediol. They claim that is what is it on the forums. I guess we will have to take their word for it.
- Fusion Supplements has not told us how much 4-Androstenediol is in each complexed tablet. It’s likely 25mg’s, but it much less for all we know at the consumer level.
As far as I know no third party has actually confirmed that this actually contains 4-androstenediol. However Fusion Supplements has posted online that it is in fact 4-androstenediol, and invited naysayers to test it. This doesnt mean much, but the clarification is helpful since the label simply says “Cyclo 4-AD”, which could mean a variety of things.
Shortly after writing the article in July, Predator Nutrition a seller of AndroTest contacted Fusion Supplements to help answer my questions. Fusion again confirmed that it was 4-androstenediol, but they also answered question #2. They indicated that the product contains 25 mg’s of active 4-androstenediol. Which is what I assumed but it is nice to have that confirmation.
Having 25 mg’s of 4-androstenediol is important, because this matches the dose used in the 2002 study that showed we could reach supraphysiological levels of testosterone using 25 mg’s of 4-AD within a cyclodextrin complex.
Fusion Supplements still says the product is intended to be oral, while the product studied in 2002 was intended as a sublingual preparation (let it dissolve under your tongue). AndroTest is in capsules, so you really can’t let it dissolve under the tongue. Nonetheless cyclodextrins work whether they are oral or sublingual.
This is because the inherent design of a cyclodextrin complex is to increase the water solubility of of the compound. Greater solubility often equals greater dissolution, and subsequently can improve overall bioavailability. Overall this seems to one of the better test base options for UK users